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Lehman College

Department of Chemistry

Naphtali A. O'Connor

Naphtali A. O'ConnorAssociate Professor
Phone: (718) 960-8678
Office: Davis Hall 326


  • B.Sc. State University of New York, Stony Brook
  • Ph.D. University of California, Irvine

Research synopsis

My current research focus is the development of materials for biomedical applications. We recently developed a method for preparing polysaccharide-polyamine crosslinked hydrogels. We are currently exploring their application as anti-microbial and wound healing materials. We are also working on the development of curcumin based biomaterials as antibacterial agents and cancer therapeutics.


  • Diana Samaroo, Evelyn Perez, Amit Aggarwal, Andrew Wills, Naphtali O’Connor “Strategies for Delivering Porphyrinoid-based Photosensitizers in Therapeutic Applications” Therapeutic Delivery (2014), 5(7), 859-872.
  • Amanda Muraca, Naphtali O’Connor, Ravnit Kaur-Bhatia, Nicoleta Apostol, Andrei Jitianu, Mihaela Jitianu “Titanium Dioxide Nanocomposites — Synthesis and Photocatalysis” Processing and Properties of Advanced Ceramics and Composites VI: Ceramic Transactions (2014) 249, 123-135.
  • Naphtali A. O’Connor, Ahmad Abugharbieh, Emmanuel Buabeng, Farzana Yasmeen, Steve Mathew, Diana Samaroo, Hai-Ping Cheng “The Crosslinking of Polysaccharides with Polyamines and Dextran-Polyallylamine Antibacterial Hydrogels” Int. J. Biol. Macromol. (2015) 72, 88-93.
  • Naphtali A. O’Connor, Gustavo E. López and Antony Cruz “Quinoline-2-thiol Derivatives as Fluorescent Sensors for Metals, pH and HNO” Current Chem. Lett. (2014) 3(3), 189-194.
  • Naphtali A. O’Connor, Navzer D. Sachinvala and Iraj Ganjian “Preparation of 2-Arylethynylselanylacetonitriles from 4-Aryl-1,2,3-Selenadiazoles” Het. Chem. (2015) 52, 1167-1169.
  • Solomon, Marissa R.; O’Connor, Naphtali A.; Paik, David C.; Turro, Nicholas J. “Nitroalcohol Induced Hydrogel Formation in Amine-Functionalized Polymers.” J. Appl. Polym. Sci. (2010), 117(2), 1193-1196.
  • O'Connor, Naphtali A.; Stevens, Stevens; Samaroo, Diana; Solomon, Marissa R.; Martí, Angel A.; Dyer, Joanne; Vishwasrao, Harshad; Akins, Daniel L.; Kandel, Eric R.; Turro, Nicholas J. “A covalently linked phenanthridine-ruthenium(II) complex as a RNA probe.” Chem. Comm. (2009), 2640-2642
  • van der Wiel, Ingrid; Cheng, Jenny; Koukiekolo, Roger; Lyn, Rodney; Stevens, Nathan; O'Connor, Naphtali; Turro, Nicholas; Pezacki, John "FLEth RNA Intercalating Probe is a Convenient Reporter for Small Interfering RNAs." J. Am. Chem. Soc. (2009), 131(29), 9872-9873
  • Berro, A.J., Gu, X., O'Connor, N., Jockusch, S., Nagai, T., Ogata, T., Zimmerman, P., Rice, B.J., Adolph, E., Byargeon, T., Gonzalez, J., Turro, N.J., Grant Willson, C. “Optical threshold layer and intermediate state two-photon PAG approaches to double exposure lithography “ Proc. SPIE (2009),7273
  • O’Connor,Naphtali A.; Bero, Adam; Lancaster, Jeffery R.; Gu, Xingu; Jockush, Steffen; Nagai, Tomoki; Ogata, Toshiyuki; Lee, Saul; Zimmerman, Paul; Willson, C. Grant; Turro, Nicholas J. “Toward a sequential two photon photoacid generator for double exposure photolithography.” Chem. Mater. (2008), 20(24), 7374-7376
  • Lancaster, Jeffrey R.;  Martí, Angel A.;López-Gejo, Juan; Jockusch, Steffen; O’Connor, Naphtali; Turro, Nicholas J. “Non-radiative deactivation of singlet oxygen (1O2) by cubane and its derivatives.” Org. Lett.  (2008), 10(24), 5509-5512
  • O’Connor, Naphtali A.; Liberman, Vladimir; Lei, Xuegong; Lopez-Gejo, Juan; Turro, Nicholas J.; Zimmerman, Paul A. “Degradation of Hydrocarbon Fluids in the Immersion Lithography at 193 nm.” J. Photopolym. Sci. Technol. (2008), 21(5), 607
  • Stevens, Nathan; O'Connor, Naphtali A.; Vishwasrao, Harshad; Samaroo, Diana; Kandel, Eric R.; Akins, Daniel L.; Drain, Charles M.; Turro, Nicholas J. “Two color RNA intercalating probe for cell imaging applications.” J. Am. Chem. Soc. (2008) 130, 7206-7207
  • Zimmerman, P. A.; Byers, J.; Rice, B.; Ober, C. K.; Giannelis, E. P.; Rodriguez, R.; Wang, D.; O'Connor, N.; Lei, X.; Turro, N. J.; Liberman, V.; Palmacci, S.; Rothschild, M.; Lafferty, N.; Smith, B. W., “Development and evaluation of a 193nm immersion generation-three fluid candidates.” Proc. SPIE (2008),6923.
  • Liberman, V.; Rothschild, M.;Palmacci, S.T.; Bristol, R.; Byers, J.; Turro, N.J., Lei, X.; O'Connor, N.; Zimmerman, P.A. “High-index immersion lithography: Preventing lens photocontamination and identifying optical behavior of LuAG” Proc. SPIE (2008),6924
  • O’Connor, Naphtali A.; Paisner, David A.; Huyrn, Donna; Shea, Kenneth J.  “Discrimination of 5HT1A Receptor Antagonists via Molecular Imprinting.” J. Am. Chem. Soc. (2007), 129(6), 1680-1689
  • O'Connor, Naphtali A.; Sakata, Steven T.; Zhu, Huide; Shea, Kenneth J.   “Chemically Modified Dansyl Probes: A Fluorescent Diagnostic for Ion and Proton Detection in Solution and in Polymers.”    Organic Letters (2006), 8(8), 1581-1584
  • Metzke, Mark; O'Connor, Naphtali; Maiti, Soumen; Nelson, Edward; Guan, Zhibin.   “Saccharide-peptide hybrid copolymers as biomaterials.”  Angew. Chem., Int. Ed. (2005), 44(40), 6529-6533
  • Edmondson, Scott D.; Mastracchio, Anthony; He, Jiafang; Chung, Christine C.; Forrest, Michael J.; Hofsess, Scott; MacIntyre, Euan; Metzger, Joseph; O'Connor, Naphtali; Patel, Kajal; Tong, Xinchun; Tota, Michael R.; Van der Ploeg, Lex H. T.; Varnerin, Jeff P.; Fisher, Michael H.; Wyvratt, Matthew J.; Weber, Ann E.; Parmee, Emma R.   “Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors.”    Bioorg. Med. Chem. Lett. (2003), 13(22), 3983-3987