Naphtali A. O'Connor

Associate Professor
Phone: (718) 960-8678
Office: Davis Hall 326


  • B.Sc. State University of New York, Stony Brook
  • Ph.D. University of California, Irvine

Research synopsis

Prof. O'ConnorMy current research focus is the development of materials for biomedical applications. We recently developed a method for preparing polysaccharide-polyamine crosslinked hydrogels. We are currently exploring their application as anti-microbial and wound healing materials. We are also working on the development of curcumin based biomaterials as antibacterial agents and cancer therapeutics.


  • Naphtali A. O’Connor, Ahmad Abugharbieh, Emmanuel Buabeng, Farzana Yasmeen, Steve Mathew, Diana Samaroo, Hai-Ping Cheng “The Crosslinking of Polysaccharides with Polyamines and Dextran-Polyallylamine Antibacterial Hydrogels” Int. J. Biol. Macromol. (2015) 72, 88-93.
  • Diana Samaroo, Evelyn Perez, Amit Aggarwal, Andrew Wills, Naphtali O’Connor “Strategies for Delivering Porphyrinoid-based Photosensitizers in Therapeutic Applications” Therapeutic Delivery (2014), 5(7), 859-872.
  • Naphtali A. O’Connor, Gustavo E. López and Antony Cruz “Quinoline-2-thiol Derivatives as Fluorescent Sensors for Metals, pH and HNO” Current Chem. Lett. (2014) 3(3), 189-194.
  • Solomon, Marissa R.; O’Connor, Naphtali A.; Paik, David C.; Turro, Nicholas J. “Nitroalcohol Induced Hydrogel Formation in Amine-Functionalized Polymers.” J. Appl. Polym. Sci. (2010), 117(2), 1193-1196.
  • van der Wiel, Ingrid; Cheng, Jenny; Koukiekolo, Roger; Lyn, Rodney; Stevens, Nathan; O'Connor, Naphtali; Turro, Nicholas; Pezacki, John "FLEth RNA Intercalating Probe is a Convenient Reporter for Small Interfering RNAs." J. Am. Chem. Soc. (2009), 131(29), 9872-9873.
  • Berro, A.J., Gu, X., O'Connor, N., Jockusch, S., Nagai, T., Ogata, T., Zimmerman, P., Rice, B.J., Adolph, E., Byargeon, T., Gonzalez, J., Turro, N.J., Grant Willson, C. “Optical threshold layer and intermediate state two-photon PAG approaches to double exposure lithography “ Proc. SPIE (2009), 7273.
  • O'Connor, Naphtali A.; Stevens, Stevens; Samaroo, Diana; Solomon, Marissa R.; Marti, Angel A.; Dyer, Joanne; Vishwasrao, Harshad; Akins, Daniel L.; Kandel, Eric R.; Turro, Nicholas J. "A covalently linked phenanthridine-ruthenium(II) complex as a RNA probe." Chem. Comm. (2009), 2640-2640.
  • O'Connor, Naphtali A.; Bero, Adam; Lancaster, Jeffery R.; Gu, Xingu; Jockush, Steffen; Nagai, Tomoki; Ogata, Toshiyuki; Lee, Saul; Zimmerman, Paul; Willson, C. Grant; Turro, Nicholas J. "Toward a sequential two photon photoacid generator for double exposure photolithography." Chem. Mater. (2008), 20(24), 7374-7376.
  • Lancaster, Jeffrey R. Marti, Angel A.; Lopez-Gejo, Juan; Jockusch, Steffen; O'Connor, Naphtali; Turro, Nicholas J. "Non-radiative deactivation of singlet oxygen (1O2) by cubane and its derivatives." Org. Lett. (2008), 10(24), 5509-5512.
  • O'Connor, Naphtali A.; Liberman, Vladimir; Lei, Xuegong; Lopez-Gejo, Juan; Turro, Nicholas J.; Zimmerman, Paul A. "Degradation of Hydrocarbon Fluids in the Immersion Lithography at 193 nm." J. Photopolym. Sci. Technol. (2008), 21(5), 607.
  • Stevens, Nathan; O'Connor, Naphtali A.; Vishwasrao, Harshad; Samaroo, Diana; Kandel, Eric R.; Akins, Daniel L.; Drain, Charles M.; Turro, Nicholas J. "Two color RNA intercalating probe for cell imaging applications." J. Am. Chem. Soc. (2008) 130, 7206-7207.
  • Zimmerman, P. A.; Byers, J.; Rice, B.; Ober, C. K.; Giannelis, E. P.; Rodriguez, R.; Wang, D.; O'Connor, N.; Lei, X.; Turro, N. J.; Liberman, V.; Palmacci, S.; Rothschild, M.; Lafferty, N.; Smith, B. W., "Development and evaluation of a 193nm immersion generation-three fluid candidates." Proc. SPIE (2008), 6923.
  • Liberman, V.; Rothschild, M.; Palmacci, S.T.; Bristol, R.; Byers, J.; Turro, N.J., Lei, X.; O'Connor, N.; Zimmerman, P.A. "High-index immersion lithography: Preventing lens photocontamination and identifying optical behavior of LuAG" Proc. SPIE (2008),6924.
  • O'Connor, Naphtali A.; Paisner, David A.; Huyrn, Donna; Shea, Kenneth J. "Discrimination of 5HT1A Receptor Antagonists via Molecular Imprinting." J. Am. Chem. Soc. (2007), 129(6), 1680-1689.
  • O'Connor, Naphtali A.; Sakata, Steven T.; Zhu, Huide; Shea, Kenneth J. "Chemically Modified Dansyl Probes: A Fluorescent Diagnostic for Ion and Proton Detection in Solution and in Polymers." Organic Letters (2006), 8(8), 1581-1584.
  • Metzke, Mark; O'Connor, Naphtali; Maiti, Soumen; Nelson, Edward; Guan, Zhibin. "Saccharide-peptide hybrid copolymers as biomaterials. "Angewandte Chemie, International Edition (2005), 44(40), 6529-6533.
  • Edmondson, Scott D.; Mastracchio, Anthony; He, Jiafang; Chung, Christine C.; Forrest, Michael J.; Hofsess, Scott; MacIntyre, Euan; Metzger, Joseph; O'Connor, Naphtali; Patel, Kajal; Tong, Xinchun; Tota, Michael R.; Van der Ploeg, Lex H. T.; Varnerin, Jeff P.; Fisher, Michael H.; Wyvratt, Matthew J.; Weber, Ann E.; Parmee, Emma R. "Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors." Bioorganic and Medicinal Chemistry Letters (2003), 13(22), 3983-3987.

Last modified: Sep 21, 2015