Faculty Pratyusha Mandal


Pratyusha Mandal E-mail address: pratyusha.mandal@lehman.cuny.edu
Phone Number: 718-960-8644
Office: Davis Hall 221A
Rank: Assistant Professor

  • Bachelor of Technology, Haldia Institute of Technology, India;
  • Ph.D. Perdue University
  • Lyons JD*C, Mandal P*C,……Mocarski ESC, Coppersmith CMC,  RIPK3 drives Pseudomonas aeruginosa-triggered pneumonia and sepsis.*co-first author Ccorresponding author. AJRCMB, 2022.
  • Mocarski, ESc, Mandal Pc, TNF-dependent hyperactivation of RIPK1- dependent cytotoxic signaling during embryogenesis and inflammation, PLoS Biol 19(8): e3001371. https:// doi.org/10.1371/journal.pbio.300137, Ccorresponding author.
  • Mandal P*C, Crosby, L*, … Mocarski ESC. Multiple Autonomous Cell Death Suppression Strategies Ensure Cytomegalovirus Fitness; Viruses 2021. *co-first author,Ccorresponding author.
  • Mandal P*C, Lyons JD*,…… Mocarski ESC, Coppersmith CMC, Integrated Evaluation of Lung Disease in Single Animals, resubmission to PLoS One, *co-first author Ccorresponding author.
  • Mandal P*, McCormick, A.L., Mocarski, ES*; TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis; Viruses, 2020. *co-corresponding authors
  • Mandal P*, Feng Y, Lyons JD, Berger SB, Otani S, DeLaney A, Tharp GK, Maner-Smith K, Burd EM, Schaeffer M, Hoffman S, Capriotti C, Roback L, Young CB, Liang Z, Ortlund EA, DiPaolo NC, Bosinger S, Bertin J, Gough PJ, Brodsky IE, Coopersmith CM, Shayakhmetov DM, Mocarski ES*. Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock. Immunity, 2018. *co-corresponding authors
  • Mandal P, Berger SB, Pillay S, Moriwaki K, Huang C, Guo H, Lich JD, Finger J, Kasparcova V, Votta B, Ouellette M, King BW, Wisnoski D, Lakdawala AS, DeMartino MP, Casillas LN, Haile PA, Sehon CA, Marquis RW, Upton J, Daley-Bauer LP, Roback L, Ramia N, Dovey CM, Carette JE, Chan FK, Bertin J, Gough PJ, Mocarski ES, Kaiser WJ., RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity. Mol. Cell, 2014.
  • Kim, E.O., Woodruff, M.C., Grigoryan, L., Maier B., Lee S.H., Mandal, P#.………..Pulendran, B. Squalene-based vaccine adjuvants stimulate CD8 T cell and antibody responses response through RIPK3-dependent pathways; eLife, 2020. #Name spelled wrong and request for correction is pending.
  • Koehler HS, Feng Y,Mandal P, Mocarski ES Recognizing limits of Z-nucleic acid binding protein (ZBP1/DAI/DLM1) function. FEBS J. 2020.
  • Ucero AC, Bakiri L, Roediger B, Suzuki M, Jimenez M, Mandal P,… Wagner EF. Fra-2 expressing -macrophages promote lung fibrosis in mice. J Clin Invest. 2019.
  • Kaiser WJ, Daley-Bauer LP, Thapa RJ, Mandal P, Berger SB, Huang C, Sundararajan A, Guo H, Roback L, Speck SH, Bertin J, Gough PJ, Balachandran S, Mocarski ES. RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition, Proc Natl  Acad Sci U S A. 2014.
  • Kaiser WJ, Sridharan H, Huang C, Mandal P, Upton JW, Gough PJ, Sehon CA, Marquis RW, …..Mocarski ES. J Biol. Chem, 2013.
  • Mandal P, Krueger BE, Oldenburg D, Andry KA, Beard RS, White DW, Barton ES., A gammaherpesvirus cooperates with interferon-alpha/beta-induced IRF2 to halt viral replication PLoS Pathog. 2011.
  • Barton E, Mandal P, Speck SH., Pathogenesis and host control of gammaherpesviruses: lessons from the mouse, Annu Rev Immunol. 2011;29:351-97.

Manuscripts submitted, resubmitted or in preparation